Skip to content
  • SUPPORT
  • QUOTE
  • REGISTER
  • LOG IN
Sable Systems International Logo
  • HOME
  • PRODUCTS
    • Overview
    • Promethion Core Line
    • Promethion Line
    • Classic Line
  • APPLICATIONS
    • Overview
    • Biomedical Research
    • Physiology
    • Environmental Research and Process Control
    • General Gas and Process Analysis
  • WHAT’S NEW
  • EDUCATION
    • Instructional Videos
    • Courses and Conferences
    • Frequently Asked Questions
    • Society Links
    • Founder’s Blog
    • Publications
  • COMPANY
    • About Us
    • Executive Team
    • History
    • News Releases
    • Careers
    • Warranty and Legal Information
    • Business Policies
  • CONTACT US

Aging, Health and Lifespan Metabolic Studies

Applications

Home/Applications/Physiology/Aging, Health and Lifespan Metabolic Studies
Aging, Health and Lifespan Metabolic StudiesJeff Richardson2020-04-03T14:24:49-07:00

Metabolic measurement plays a critical role in aging research as the community seeks to understand the healthspan and lifespan trade-offs of the aging process. Recent integrated research from model animals to humans has applied indirect calorimetry to further understand the relationship of cardiovascular disease, insulin resistance, metabolic syndrome and diabetes to senescence. From such a research platform we can better consider which interventions can effectively mitigate age related disease.

Salient Features

  • Precise calorimetry, food and water intake measurements
  • High temporal resolution for circadian studies
  • Instrumentation scales from Drosophila to human
  • High-throughput and workflow efficiency
  • GLP compliant solutions, animal safety focus
  • Activity monitoring with Ethogram capability

Sable Solutions

Drosophila Metabolic Screening System

Depending on the method used, Sable Drosophila metabolic screening systems are capable of measuring the metabolic rates of small groups of Drosophila, or even of individual Drosophila in real time. This unique ... (more)

MAVEn™ System for Small Insect Flow-Through Respirometry

The Sable MAVEn™ system is an integrated, compact 16-channel flow generator for small insect flow-through respirometry. Each flow is pushed through a sealed container holding a subject animal. The system automatically selects ... (more)

Promethion Core Behavioral Phenotyping Mouse System

The Promethion Core Behavior Phenotyping System features the modular flexibility to support real-time behavioral studies in a home-cage setting. Capture a complete data-rich archive of behaviors with unbeatable temporal resolution. Second-by-second observations ... (more)

Promethion High-Definition Behavioral Phenotyping System for Rats

The Promethion line features the modular flexibility to support real-time behavioral studies in a home-cage setting with a small sample size or large-scale neurophysiological, pharmacokinetic and toxicological studies. Our high-definition behavioral phenotyping ... (more)

Promethion High-Definition Room Calorimetry System

The Promethion High-Definition Room Calorimetry System is capable of synchronously recording all measured parameters in a completely traceable manner. Key components of this system include the GA-3m2 triple gas O2, CO2, and ... (more)

Contact Us

Our systems are highly customizable for a broad range of applications. Let us help configure a system to meet your specific research needs.

Help Me Configure a System

Relevant Publications

Csóka, B., Koscsó, B., Törő, G., Kókai, E., Virág, L., Németh, Z. H., … & Haskó, G. (2014). A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation. Diabetes, 63(3), 850-866.

Icreverzi, A., de la Cruz, A. F., Van Voorhies, W. A., & Edgar, B. A. (2012). Drosophila cyclin D/Cdk4 regulates mitochondrial biogenesis and aging and sensitizes animals to hypoxic stress. Cell Cycle, 11(3), 554-68.

Lane, S. J., Frankino, W. A., Elekonich, M. M., & Roberts, S. P. (2014). The effects of age and lifetime flight behavior on flight capacity in Drosophila melanogaster. The Journal of experimental biology, 217(9), 1437-1443. [and see Controlled Atmospheres applications]

Stern, J. H., Kim, K., & Ramsey, J. J. (2012). The influence of Shc proteins and aging on whole body energy expenditure and substrate utilization in mice. PloS one, 7(11), e48790.

Wit, J., Sarup, P., Lupsa, N., Malte, H., Frydenberg, J., & Loeschcke, V. (2013). Longevity for free? Increased reproduction with limited trade-offs in Drosophila melanogaster selected for increased life span. Experimental gerontology, 48(3), 349-357.

Sable Enables

Before configuring any system, we strive to understand your application. Our innovative instruments and analysis tools are then configured and customized for your application, providing you sound results and efficient workflow.

What’s New

  • Inside Scientific Webinar – Comfort Food: Effects of Stress and High-Fat Diets on Neuronal Activity and Mitochondrial Remodeling in Mice

    Inside Scientific Webinar – Comfort Food: Effects of Stress and High-Fat Diets on Neuronal Activity and Mitochondrial Remodeling in Mice

    February 5, 2021
  • Inside Scientific Webinar: Sex, Sugar, Fat, and Heat: Factors That Affect Energy Budgets, Weight Management and Behaviors in Mice

    Inside Scientific Webinar: Sex, Sugar, Fat, and Heat: Factors That Affect Energy Budgets, Weight Management and Behaviors in Mice

    October 24, 2020
  • Inside Scientific Webinar: From Pregnancy to Menopause – Studies of Physical Activity, Behavior, and Energy Balance in Mice

    Inside Scientific Webinar: From Pregnancy to Menopause – Studies of Physical Activity, Behavior, and Energy Balance in Mice

    October 5, 2020
  • Promethion® Isocage Negative Pressure Mouse Cage

    Promethion® Isocage Negative Pressure Mouse Cage

    September 11, 2020

UPCOMING EVENTS

Mar
9
Tue
1:00 pm Comfort Food: Effects of Stress ... @ Inside Scientific Webinar
Comfort Food: Effects of Stress ... @ Inside Scientific Webinar
Mar 9 @ 1:00 pm – 2:00 pm
 
View Calendar

UPCOMING CONFERENCES

There are no upcoming events.

View Calendar

By Scientists.
For Scientists.

We encourage you to discuss
your application with us.

+1 800 330 0465
+1 702 269 4445

+1 702 269 4446

Contact Directory
sales@sablesys.com
support@sablesys.com

Sable Systems International

3840 N. Commerce Street
North Las Vegas, NV 89032
USA
More Information

Sable Systems Europe

Contact international offices

PRIVACY POLICY
TERMS OF USE

© Copyright 2020 Sable Systems. All rights reserved.
twitterfacebookyoutubelinkedin