The “Deep Data Field System” in Metabolic Phenotyping

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Activity Metabolism Measurements Made Easy in Metabolic Phenotyping

One of the classic controversies in the field of metabolic science is the effect of activity on overall energy expenditure. As a comparative physiologist with a long-standing interest in energetics (and several papers published in that field), I find this controversy to be particularly strange, especially because some respectable and intelligent people will politely insist…

How Multiplexing Distorts Metabolic Phenotyping Data

Multiplexing metabolic signals causes significant data distortion. This post explains how, and gives you access to an amazing, interactive tool for exploring the metabolic data distortions produced by this practically universally-used technique! To save cost, almost all metabolic phenotyping systems multiplex their gas analyzers, so that the air streams from the metabolic chambers are analyzed in succession….

Three reasons for misleading gas analyzer accuracy specifications

A funny thing happened on my way to helping a colleague make sense of the specifications of a metabolic phenotyping system. There were many strange things to mull over. Not the least of these were oxygen and carbon dioxide analyzer accuracy specifications that appeared to be the product of smoke, mirrors, and absinthe-infused coca tea…

Measuring food uptake differentially

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Data, data, data!

This shows a day’s worth of data from a single mouse in graphic form, recorded by a Promethion-C system for a research study on which I’m collaborating. The time resolution of the data set is one second. Loads of additional data (such as XY position and so on) didn’t make it into the graph but are…

Automated behavior analysis: The basics of EthoScan

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