New FMS-Mouse Metabolic Treadmill System for Induced Exercise Studies

Sable Systems International, the leader in animal metabolism research systems, is pleased to announce the launch of its new FMS-Mouse Metabolic Treadmill System. This innovative system empowers researchers to conduct cardiovascular fitness tests such as graded exercise and progressive exercise tests, similar to human fitness tests. These tests provide fitness parameters such as VO2max, metabolic crossover, anaerobic threshold, and time to exhaustion – advancing understanding of the physiological response to exercise with the aim of reducing the prevalence of metabolic diseases. 

The FMS-Mouse Metabolic Treadmill System represents a powerful integration of Sable’s renowned technologies. It combines the compact and fully integrated FMS indirect calorimeter, the high-performance Sable Mouse Metabolic Treadmill, and the easy-to-use Expedata data acquisition and analysis software to deliver a complete and streamlined solution for exercise research. 

Increasing demand for mouse metabolic/behavioral phenotyping and exercise studies necessitates the need for a dedicated, high-performance mouse metabolic treadmill. No longer do scientists have to choose between their Promethion Core phenotyping research and treadmill exercise studies. As a dedicated mouse metabolic treadmill, this system enables Promethion researchers to do both at once. For researchers who do not have a Promethion Core System, this new treadmill offering is a cost-effective approach with the same high-performance.

This new system provides unparalleled flexibility for designing sophisticated exercise protocols. The ability to finely control speed, acceleration, and incline, coupled with a wide range of adjustable parameters, allows researchers to tailor experiments precisely to their research questions. The automated treadmill controller and unique chamber leveling feature ensure exceptional accuracy and reliability, providing researchers with trusted results.

The treadmill offers four selectable stimuli: electric shock, light, sound, and a manual push brush, accommodating diverse experimental designs and individual animal responses. Furthermore, the system simplifies data management and analysis. Treadmill output and metabolic measures are seamlessly integrated into Sable’s Expedata software, eliminating the need for time-consuming data merging and synchronization. Treadmill data can be visualized during ongoing data acquisition, allowing researchers to monitor and manage their experiments.