The Promethion Core Metabolic System gives you the truest and most trustworthy results from your rodent phenotyping studies. At the heart of the system is the highest resolution metabolic measurement instrumentation, yielding accurate resting and active energy expenditure values.
Then we add second-by-second behavioral measurements, providing the highest data granularity. Promethion Core tightly synchronizes all data (metabolic and behavioral), allowing you to pinpoint and correlate metabolic change with each behavioral event. All the raw data is saved for further data mining.
Other systems try to match Promethion Core’s performance by employing an oversampling technique, for example, continuous gas measurements of each cage. But due to these systems’ low-resolution gas analyzers and requisite slow air-exchange rates, continuous oversampling simply results in useless and redundant data (see video “The Effects of Cage Air-Flow Rate”).
The entire system is compact and self-contained to save valuable lab space, allowing up to 16 cages in an environmental cabinet. This provides 33% more housed cages than competitor systems, maximizing your experimental power. Your workflow is efficient with swappable components and magnetic mounts for quick exchange of hoppers and measurement devices.
The new Promethion Live software enables you to control all aspects of your study. The simplified interface maximizes experiment success with intuitive system and experiment setup. One-step gas calibration ensures accurate respirometry measurements. Status indicators for vital components verify system performance. Constant monitoring of all parameters means you will always know the well-being of each animal. Routine experiment configurations can be easily saved and reused.
With Promethion Live, you can explore comparative trends during an experiment looking at every parameter measured, such as running speed, food consumed, or energy expended (data shown). The software uniquely provides the mean (± SD; ± SEM) or median of grouped data for real-time statistical comparison and experiment evaluation. You’re empowered with the real-time experiment and animal information needed to make key decisions at any time, from any place.
Promethion Core Instrumentation includes:
Triple Gas Single Path Analyzer
8-channel Flow Generator and Multiplexer
Promethion Live onboard computer and memory
Standard size home cage
Precision Mass Monitors
Magnetic Mount Food Hopper
Magnetic Mount Water Bottle with Sipper Tube
2- or 3-Dimensional Infrared Beam Break Array
Promethion Live Software Platform
Desktop Computer with Monitor
Body Mass Habitat
Access Control Door for Food Hopper or Water Bottle
Environmental Sensor Array
Environmental Control Cabinet
Telemetry Bases for Body Temperature and Heart Rate
Stable Isotope Analyzer (13CO2)
Optogenetic Compatible Cage Lid
For a custom configuration, contact us and our specialists will help you configure the right system for your specific research needs.