Description
Real-time measurement of discrete, small quantities of methane
The new Promethion Methane Gas Analyzer is a cutting-edge upgrade to our Promethion™ Core systems. Our methane analyzer is the only one available with the resolution and sensitivity to meet the demanding application of flow through respirometry. The methane analyzer data is synchronously added to the Promethion Core metabolic and behavioral data as well as the Promethion Stable Isotope Analyzer data.
Methane production from 5 mice. Mice 1 and 5 produced methane whereas mice 2, 3 and 4 produced almost no methane and no episodic releases.
Using this device with Promethion Core and the Stable Isotope Analyzer, a myriad of metabolic studies are now available including experimental manipulations of diet, pharmaceuticals, microbiome, transgenics, exercise, thermal exposure, age, and sex. For gnotobiotic studies, mice can be housed in our pathogen free isolation cages.
Experimental metrics include the number and magnitude of individual methane events, constitutive methane production, and cumulative methane production.
Human and other large animals – Measure constitutive methane production from breath in real time
Methane (red) and carbon dioxide (blue) production from a human before, during and after exercise. Both gasses were sampled continuously.
The Methane Analyzer can be coupled with the FMS indirect calorimetry system or the Promethion Room Calorimetry system for humans or when high resolution flow through measurements are required. The gas collection interface can be a mask, canopy, or custom enclosure.
