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Slide Exercise Biology

Applications

Home/Applications/Biomedical Research/Exercise Biology
Exercise BiologyJeff Richardson2022-03-25T10:14:03-07:00

Exercise is considered a key tool in the prevention or treatment of metabolic disorders. Exercise powerfully affects energy balance. Besides the changes caused by a single exercise session, regular exercise induces chronic adaptations, improving exercise capacity and affecting energy balance.

Exercise affects many aspects of physiology. Therefore, the study of the effects of exercise in human and animal models is greatly benefited by comprehensive phenotyping. Comprehensive phenotyping includes changes in metabolism, ingestive behavior, and activity. This enables researchers to better understand how exercise helps to prevent or treat metabolic disorders and improve the human condition.

Important System Considerations

  • Metabolic measurement (RER, VO2, VCO2)
  • Specific nutrient utilization
  • Food and water intake with automated access control
  • Activity monitoring, total and running

Sable Solutions

CAB-8 and CAB-16 Environmental Control Cabinets

The CAB-8 and CAB-16 provide environmental control for your Promethion Core rodent metabolism and behavioral system. These cabinets provide up to 100 user-defined changes in temperature and light intensity over the course ... (more)

Promethion Core Line

The new Promethion Core™ is the first and only metabolic and behavioral measurement system that utilizes modern digital and computer technology to deliver the highest resolution data regardless of study size. This ... (more)

Promethion High-Definition Room Calorimetry System

The Promethion High-Definition Room Calorimetry System is capable of synchronously recording all measured parameters in a completely traceable manner. Key components of this system include the GA-3m2 triple gas O2, CO2, and ... (more)

Sable Metabolic Treadmill

The Promethion Core Behavior Phenotyping System features the modular flexibility to support real-time behavioral studies in a home-cage setting. Capture a complete data-rich archive of behaviors with unbeatable temporal resolution. Second-by-second observations ... (more)

Stable Isotope Gas Analyzer

Continuous measurement of 13C and 18O isotopes in exhaled breath The new Stable Isotope Gas Analyzer is a cutting-edge upgrade to our standard Promethion™ systems, allowing simultaneous measurement of stable isotope tracers synchronously ... (more)

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Relevant Publications

Publications Filter - Applications Page - Exercise Biology

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12 Results Found (Showing 1 - 6)

COX7A2L genetic variants determine cardiorespiratory fitness in mice and human. Benegiamo G, Sleiman MB, Wohlwend M, Rodríguez-López S, Goeminne LJE., Laurila PP, Klevjer M, Salonen MK, Lahti J, Jha P, Cogliati S, Enriquez JA, Brumpton BM, Bye A, Eriksson JG & Auwerx J. Nature Metabolism. 10/17/2022.

October 17, 2022 12:00 am Published by Brett Davis

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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function. Blazev R, Carl C, Ng Y, Molendijk J, Voldstedlund CT, Zhao Y, Xiao Di, Kueh AJ, Miotto PM, Haynes VR, Hardee JP, Chung JD, McNamara JW, Qian H, Gregorevic P, Oakhill JS, Herold MJ, Jensen TE, Lisowski L, Lynch GS, Dodd GT, Watt MJ, Yang P, Kiens B, Richter EA, Parker BL. Cell Metabolism. 7/25/2022.

July 25, 2022 12:00 am Published by Brett Davis

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Exercise May Ameliorate the Detrimental Side Effects of High Vitamin D Supplementation on Muscle Function in Mice. Debruin DA, Timpani CA, Lalunio H, Rybalka E, Goodman CA, Hayes A. Journal of Bone and Mineral Research. 6/6/2020.

June 6, 2020 12:00 am Published by Brett Davis

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Mitochondrial adaptations to exercise do not require Bcl2-mediated autophagy but occur with BNIP3/Parkin activation. Ehrlicher SE, Stierwalt HD, Miller BF, Newsom SA, Robinson MM. Federation of American Societies for Experimental Biology. 1/17/2020.

January 17, 2020 12:00 am Published by Brett Davis

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IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism. Regué L, Ji F, Flicker D, Kramer D, Pierce W, Davidoff T, Widrick JJ, Houstis N, Minichiello L, Dai N, Avruch J. American Society for Microbiology. 4/1/2019.

April 1, 2019 12:00 am Published by Brett Davis

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Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise. Lark DS, Kwan JR, McClatchey M, James MN, James FD, Lighton JRB, Lantier L, Wasserman DH. American Diabetes Association. 5/1/2018.

May 1, 2018 12:00 am Published by Brett Davis

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