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Slide Microbiome

Applications

Home/Applications/Biomedical Research/Microbiome
MicrobiomeBrett Davis2022-03-25T10:16:28-07:00

Progress in the study of metabolomics has opened a new door to understanding the relationship between the microbiome and host. Studies in rodents indicate that the bidirectional signaling between the intestine and the brain plays an important role in the regulation of both metabolism and behavior. Metabolic and behavioral phenotyping systems coupled with the ability to trace the utilization of specific nutrients provide ideal platforms for research in this area.

Important System Considerations

  • Metabolic measurement
  • Behavioral measurement including food and water intake
  • Trace specific nutrients through metabolic pathways
  • Controlled environment
  • Food and water access control

Sable Solutions

Promethion Core Line

The new Promethion Core™ is the first and only metabolic and behavioral measurement system that utilizes modern digital and computer technology to deliver the highest resolution data regardless of study size. This ... (more)

Promethion High-Definition Room Calorimetry System

The Promethion High-Definition Room Calorimetry System is capable of synchronously recording all measured parameters in a completely traceable manner. Key components of this system include the GA-3m2 triple gas O2, CO2, and ... (more)

Stable Isotope Gas Analyzer

Continuous measurement of 13C and 18O isotopes in exhaled breath The new Stable Isotope Gas Analyzer is a cutting-edge upgrade to our standard Promethion™ systems, allowing simultaneous measurement of stable isotope tracers synchronously ... (more)

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Relevant Publications

Publications Filter - Applications Page - Microbiome

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Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection. Zhang W, Lyu M, Bessman NJ, Xie Z, Arifuzzaman M, Yano H, Parkhurst CN, Chu C, Zhou L, Putzel GG, Li T-T, Jin W-B, Zhou J, JRI Live Cell Bank, Hu H, Tsou AM, Guo CJ, Artis D. Cell. 10/27/2022.

October 27, 2022 12:00 am Published by Brett Davis

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Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation. Wong CK, Yusta B, Koehler JA, Baggio LL, McLean BA, Matthews D, Seeley RJ, & Drucker DJ. Cell Metabolism. 10/4/2022.

October 4, 2022 12:00 am Published by Brett Davis

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The microbiota regulate neuronal function and fear extinction learning. Chu C, Murdock MH, Jing D, Hyung Won T, Chung H, Kressel AM, Tsaava T, Addorisio ME, Putzel GG, Zhou L, Bessman NJ, Yang R, Moriyama S, Parkhurst CN, Li A, Meyer HC, Teng F, Chavan SS, Tracey KJ, Regev A, Schroeder FC, Lee FS, Liston C, Artis D. Nature. 10/1/2019.

October 1, 2019 12:00 am Published by Brett Davis

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The gut microbiome regulates host glucose homeostasis via peripheral serotonin. Martin AM, Yabut JM, Choo JM, Page AJ, Sun EW, Jessup CF, Wesselingh SL, Khan WI, Rogers GB, Steinberg GR, Keating DJ. Proceedings of the National Academy of Sciences of the United States of America. 9/16/2019.

September 16, 2019 12:00 am Published by Brett Davis

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Investigation of the Effects of Microbiota on Exercise Physiological Adpation, Performance, and Energy Utilization Using a Gnotobiotic Animal Model. Huang WC, Chen YH, Chuang HL, Chiu CC, Huang CC. Frontiers in Microbiology. 8/20/2019.

August 20, 2019 12:00 am Published by Brett Davis

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Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice. Staffas A, Burgos de Silva M, Slingerland AE, Lazrak A, Bare CJ, Holman CD, Docampo MD, Shono Y, Durham B, Pickard AJ, Cross JR, Stein-Thoeringer C, Velardi E, Tsai JJ, Jahn L, Jay H, Lieberman S, Smith OM, Pamer EG, Peled JU, Cohen DE, Jenq RR, van den Brink MRM. Cell Host & Microbe. 4/11/2018.

April 11, 2018 12:00 am Published by Brett Davis

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