Promethion Isocage for Mice

For gnotobiotic, microbiome and pathogen isolation studies

Promethion Isocage for Mice

For gnotobiotic, microbiome and pathogen isolation studies

Features        Description       Specs        Downloads       Contact Us       Sable Enables

Features      Description     Specs      Downloads     Contact Us     Sable Enables


  • Dual incurrent HEPA filtration isolates the research animal from airborne pathogens
  • Excurrent HEPA filter keeps pathogens in the cage
  • Negative pressure airflow ensures pathogens in the cage only exit through the excurrent outlet port and HEPA filters
  • Integrates with Promethion Core metabolic measurement systems
  • Food and water are magnetically attached to the lid simplifying cage cleaning and animal maintenance


Only Sable Systems offers metabolic and behavioral phenotyping systems with a negative pressure pathogen isolation cage, providing HEPA filtration on both incurrent and excurrent air flows to keep microbes contained and researchers safe. The Promethion Isocage is ideal for metabolic and behavioral studies using mice that are germ-free, have a defined gut microbiome, or are immunocompromised. Changes in the gut microbiome may be exclusively quantified with our new, high-resolution methane gas analyzer.

The isocage delivers the same behavioral measurements as our standard cage. It is a Tecniplast Isocage-P equipped with a running wheel and magnetically mounted food hopper, water bottle, and body mass habitat built into the cage lid, simplifying cage cleaning and animal maintenance. The Promethion Isocage connected to the Promethion Core metabolic and behavioral phenotyping system creates a stress-free environment with high air-flow rates, air-flow rates, providing the highest resolution and most accurate measurements.


  • Microbiome research
  • Ingestive Behavior
  • Brown Adipose Tissue research
  • Activity and Exercise Studies
  • High Fat Diet Studies
  • Obesity and Diabetes Research
  • Aging and Longevity Research
  • Toxicology and Immunological Studies
  • SARs-Cov-2 studies
  • Virology research

System Accessories

  • Promethion Methane Gas Analyzer
  • Promethion Stable Isotope Gas Analyzer
  • Mass Measurement Device
  • Dual Access Control Lid
  • Beam Break Array
  • Temperature Control Cabinet
  • Environmental Sensor Array
  • Telemetry for Heart Rate and Temperature
  • Running Wheel with Wheel Stop
  • Specialized Food Grills

View map of Promethion Core and Promethion Room Calorimetry academic installations


Tub Specifications
Material High-Temp Polysulfone (BPA free;
autoclave up to 131˚ C)
Floor Area 82 in2 (530 cm2)
Dimensions (W x D x H) 8.1 x 14.4 x 5.5 in. (21 x 37 x 14 cm)
Weight 1.3 lb (0.6 kg)
Lid Specifications
Material Stainless Steel (autoclave up to 134˚ C)
Lid Types Solid, Wire, Vented
Accessory Mounting 3 (mounting brackets included)


contact us

Please fill out the form here and our specialists will help configure the right system for your needs or provide you with a detailed quote.

To request manuals and software updates, or find warranty and service information, please contact our Support department.