Neuroscience

Changes in neurological function may be produced by metabolic disease, neural injury, epigenetic causes, antibiotic history or exposure to toxins or treatments. Persistence and scientific rigor are a pre-requisite in this field where relevant patterns must be discerned from small signals. Metabolic assays and ethographic profiling of behavior are key methods when a high-definition, in-vivo record is required to evaluate efficacy in pharmaceutical safety, neurological or physiological investigations.

Promethion Core Behavioral System, Mouse

The Promethion Core Behavior Phenotyping System features the modular flexibility to support real-time behavioral studies in a home-cage setting. Capture a complete data-rich archive of behaviors with unbeatable temporal resolution. Second-by-second observations ... (more)

Promethion Core Metabolic System, Mouse

The Promethion Core High Definition Multiplexed Respirometry System for mice synchronously measures energy expenditure, RQ, VO2, VCO2 and activity. The SableHD™ High Definition platform updates once per second for all sensors in ... (more)

Rat GRID System

The new Promethion Rat GRID system provides automated analysis of ingestive behavior for up to 6 rats in a single spacious cage. Individual animal intake events are identified using RFID technology via ... (more)

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Promethion Core Behavioral System, Mouse

Promethion Core Metabolic System, Mouse

Rat GRID System

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Relevant Publications

Publications Filter - Applications Page - Neuroscience

Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity. Dodd GT, Xirouchaki CE, Eramo M, Mitchell CA, Andrews ZB, Henry BA, Cowley MA, Tiganis T. Cell Reports. 9/10/2019.

Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity. Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS. The Journal of the Federation of American Societies for Experimental Biology. 7/24/2019.

Functional Ontogeny of Hypothalamic Agrp Neurons in Neonatal Mouse Behaviors. Zimmer MR, Fonseca AHO, Iyilikci O, Dai Pra R, Dietrich MO. Cell. 6/27/2019.

Role of SOCS3 in POMC neurons in metabolic and cardiovascular regulation. Wang Z, do Carmo JM, da Silva AA, Bailey KC, Aberdein N, Moak SP, Hall JE. American Journal of Physiology. 1/23/2019.

Leptin Signaling in the Arcuate Nucleus Reduces Insulin’s Capacity to Supress Hepatic Glucose Production in Obese Mice. Balland E, Chen C, Dodd GT, Conductier G, Coppari R, Tiganis T, Cowley MA. Cell Reports. 1/8/2019.

Arcuate nucleus and lateral hypothalamic CART neurons in the mouse brain exert opposing effects on energy expenditure. Farzi A, Lau J, Kin Ip C, Qi Y, Shi Y-C, Zhang L, Tasan R, Sperk G, Herzog H. eLIFE. 8/21/2018.