Changes in brain function may be produced by metabolic disease, neural injury, epigenetic causes, antibiotic history or exposure to toxins or treatments. Persistence and scientific rigor are a pre-requisite in this field where relevant patterns must be discerned from small signals. Metabolic assays such as respirometry and ethographic profiling of behavior are key methods when a high-definition, in-vivo record is required to evaluate efficacy in pharmaceutical safety, neurological or physiological investigations.
Salient Features
- Behavioral systems including food choice
- High-throughput capacity, up to 128 animals.
- Second by second quantification of activity
- Automated monitoring of food and water uptake amounts and event frequency
- Differentiate between food uptake and food stashing
- Differentiate between large ingested meals from micro meals
- Interchangeable instrumentation between mouse and rat cages
- Compatibility with leading video analysis systems
Sable Solutions
Promethion Line
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Relevant Publications
Shechter, A., Rising, R., Albu, J. B., & St-Onge, M. P. (2013). Experimental sleep curtailment causes wake-dependent increases in 24-h energy expenditure as measured by whole-room indirect calorimetry. The American journal of clinical nutrition, 98(6), 1433-1439.
Kocalis, H. E. (2012). The role of neuronal peroxisome proliferator-activated receptor delta in diet-induced obesity and hypothalamic inflammation (Doctoral dissertation, Vanderbilt University).
