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  • Neuroscience and Toxicology: Behavioral and Metabolic Assays
  • Neuroscience and Toxicology: Behavioral and Metabolic Assays

Applications

Home/Applications/Biomedical Research/Neuroscience and Toxicology: Behavioral and Metabolic Assays
Neuroscience and Toxicology: Behavioral and Metabolic Assays sable_admin 2018-04-23T19:00:00+00:00

Changes in brain function may be produced by metabolic disease, neural injury, epigenetic causes, antibiotic history or exposure to toxins or treatments. Persistence and scientific rigor are a pre-requisite in this field where relevant patterns must be discerned from small signals. Metabolic assays such as respirometry and ethographic profiling of behavior are key methods when a high-definition, in-vivo record is required to evaluate efficacy in pharmaceutical safety, neurological or physiological investigations.

Salient Features

  • Behavioral systems including food choice
  • High-throughput capacity, up to 128 animals.
  • Second by second quantification of activity
  • Automated monitoring of food and water uptake amounts and event frequency
  • Differentiate between food uptake and food stashing
  • Differentiate between large ingested meals from micro meals
  • Interchangeable instrumentation between mouse and rat cages
  • Compatibility with leading video analysis systems

Sable Solutions

Promethion Core Line

The new Promethion Core™ is the first and only metabolic and behavioral measurement system that utilizes modern digital and computer technology to deliver the highest resolution data regardless of study size. This ... (more)

Promethion Line

Promethion systems capture synchronized metabolic and behavioral information, yielding a highly-resolved and uniquely rich data stream.  We offer multiplexed systems with multiple cages sharing a gas analyzer chain, offering cycle times up ... (more)

Contact Us

Our systems are highly customizable for a broad range of applications. Let us help configure a system to meet your specific research needs.

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Relevant Publications

Shechter, A., Rising, R., Albu, J. B., & St-Onge, M. P. (2013). Experimental sleep curtailment causes wake-dependent increases in 24-h energy expenditure as measured by whole-room indirect calorimetry. The American journal of clinical nutrition, 98(6), 1433-1439.

Kocalis, H. E. (2012). The role of neuronal peroxisome proliferator-activated receptor delta in diet-induced obesity and hypothalamic inflammation (Doctoral dissertation, Vanderbilt University).

Sable Enables

Before configuring any system, we strive to understand your application. Our innovative instruments and analysis tools are then configured and customized for your application, providing you sound results and efficient workflow.

What’s New

  • New 2nd Edition “Measuring Metabolic Rates – A Manual for Scientists”

    New 2nd Edition “Measuring Metabolic Rates – A Manual for Scientists”

    January 14, 2019
  • Sable Systems to Preview 2nd Edition Book and New Products at SICB Meeting, January 3-7, 2019

    Sable Systems to Preview 2nd Edition Book and New Products at SICB Meeting, January 3-7, 2019

    December 20, 2018
  • New Mouse Respirometry Treadmill

    New Mouse Respirometry Treadmill

    December 20, 2018
  • New Stable Isotope Gas Analyzer

    New Stable Isotope Gas Analyzer

    December 20, 2018

UPCOMING COURSES

Feb
26
Tue
all-day High-Throughput Respirometry for... @ Las Vegas, NV
High-Throughput Respirometry for... @ Las Vegas, NV
Feb 26 – Mar 1 all-day
This respirometry course – held in Las Vegas, NV – teaches participants how to use indirect calorimetry in metabolic screening.  We will apply techniques for measuring real-time O2 consumption, CO2 production and water vapor loss for laboratory rodents.  Measurement systems also include food & water intake, body mass monitoring, wheel running and voluntary activity. Data[...]
Mar
26
Tue
all-day An Introduction to Animal Respir... @ Las Vegas, NV
An Introduction to Animal Respir... @ Las Vegas, NV
Mar 26 – Mar 29 all-day
This respirometry course – held in Las Vegas, NV – teaches participants how to measure metabolic rates using indirect calorimetry. We will apply techniques for measuring real-time O2 consumption, CO2 production and water vapor loss for subjects ranging from small invertebrates to large mammals. Participants can work with single animal and high through-put systems in both open-flow[...]
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UPCOMING CONFERENCES

Mar
27
Wed
all-day 60th Annual Drosophila Research ... @ Sheraton Dallas Hotel
60th Annual Drosophila Research ... @ Sheraton Dallas Hotel
Mar 27 – Mar 31 all-day
Conference Website
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For Scientists.

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+1 702 269 4445

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